I've ridden the '06 on some tight trails and taken its owner on some nasty trails. That motor is so impressive, I did not feel in need of a 5 speed.
The one I rode had the suspension done and was set up for MX, but I was very impressed with how it worked on the trail. The pegs seemed high to me, but I was able to hop on the bike and immediately go well on true single track.
I hear the dealers are making deals on left-over '06's. At the right price, I would take an '06 even if trails were all I ever rode. As for MX, the 450s have a huge motor advantage on any 250 two stroke. The KX450 is strong, that's for sure.