I have not heard of the two weights in TwinChambers...hummm...where did this come from? Curious.... :think
As far as changing weights goes, what I have noticed is when going to a heavier oil (5-ATF for instance) that, as Marcus indicated the greatest effect was in the LS range. The clickers do have a greater "range" with the heavier oil though, meaning that each click is a slightly greater change than with the lighter oil, and that because of this, a couple of clicks of adjuster makes up for the slightly greater LS created by the heavier oil. In the higher speed ranges, the effect is minimal at best.