I am driving from Winnipeg, Manitoba to Apache Junction, Arizona. Google Maps and Mapquest give me a few options, the two most reasonable appear to be:
Option A - South on I-29 to I-80.
Option B - South on I-29 to I-90 to US 183 to US18 to US83 and finally to I-80.
Option B is close to 100 miles shorter but estimated time is similar likely due to being off the Interstate.