Depends on what the screw/bolt is inserted into. Any screw/bolt that inserts into a nut, I replace the nut with a Nylock nut. The Nylock nuts have a plastic insert that really cinches the screw/bolt and prevents them from vibrating loose. Nylock nuts should have won the Nobel peace prize :worship: !!!
I use to have a big problem with the screws/bolts from the side panels and pipe mounts vibrating loose. Lock washers fix these problems rather well.
All other applications, use Loctite Blue !!!