A few things:
---Grind the sharp edge off of the shifter, it'll go through the cover in a bad dump.
---Rejet to 160mj/ stock pilot with stock exhaust and lid removed
---Rejet to 165mj/ 45 pilot with new exhaust and lid removed.
---I have the model EKP needle in it. It is a yamaha part, a fatter needle than the OXBN (stock) needle. Gives a bigger midrange pull. I don't have the part number on hand, I'll get it though. It's like 11 bucks at a Yammie dealer, sudco.com may have it or carbparts.com.
---Taller handle bars are needed if over 5'9 or so, Jimmy Button renthals are the tallest (and best, IMO)
---Extended shifter may be needed too (bajadesigns)
---BK mod (limits the "squirt" in the carb, reduces off idle bog to minimum, do a search or go to thumpertalk.com)
---Keep an eye on the water pump cover, some of them weep alittle bit.
---A good skid plate (bajadesigns is the best bang for the buck)
---Thumpertalk also has cool ign/clutch cover gaurds, better than the Bajadesigns ones.
---Watch the battery, some have had problems with it draining.
As far as changing the oil, do it earlier than every 800-1000 miles! That is a very long stretch for a dirtbike! I change mine every 15 hours of riding.
Use non-synthetic until FULLY broken in, then switch to a high grade synthetic. This will keep power/shifting to a premium.
Lets see, what else...the valve that tightens up first is the right intake, uh...oh yeah, the suspension is a little bit soft. If over 180lbs or so, new springs/revalve of suspenders will be needed for racing. If under 180, maybe a revalve only. THis is only neccesary for big jumps/racing.
I have the 2001 DRZ400E, about 2000 miles or so, all off-road. I am 240 lbs/ 6 foot, I did not do the suspension and I have lived with it. It truly is a great bike, I have not had ANY problems with my bike. I do kinda beat on it too, I use WOT about 70% of the time I'd say. I have only done basic maitenance, very miticulous about it though.
Most importantly, HAVE FUN!!! :)