I ride a RM125, and I love it. It is my first ever bike, never ridden on any other bike (only automatic 4-wheelers), so I had to learn to clutch and shift, as well as keep this thing upright, all at the same time. Took a total of about..10 minutes
It has tons of power behind it (only has aftermarket exhaust), except when coming out of a tight turn gotta really pull the clutch back to keep it from bogging. From what I hear, 250's dont have that problem, and obviously have more power.
My uncle is around the same size as you and has a YZ250. The one major thing he has said is on the YZ, you just have to watch out for the powerband as it usually kicks, hard. Other than that, the 250 it a blast - just aim it where you want to go and hold on! If you are up for that, try it out.
First and foremost, you should try and find someone that will let you ride their 125 and/or 250 to see how they feel to you. I am taller than you, but much lighter, and the 125 has more than enough power for what I need right now. With your weight though, a 250 might have that extra oomph that you are looking for.
I'm a 2-stroke guy as well, as you can tell. If you want easy repairs and a get-up-and-go bike get a 2 stroke. If you want to dump hundreds into your bike every time you have to replace a piston, go for a 4T.